Choose the incorrect statement w.r.t. AIDS

Options

A. Viral RNA genome is converted into copy DNA by reverse transcriptase
B. It is caused by retrovirus HIV
C. It is an immunodeficiency disease
D. HIV selectively infects and kills B-lymphocytes

Answer

To solve the question of choosing the incorrect statement with respect to AIDS, let's break down the information step by step:

### Step 1: Understand what AIDS is
AIDS stands for Acquired Immunodeficiency Syndrome. It is a condition that results from the infection of the human immunodeficiency virus (HIV).

**Hint:** Remember that AIDS is a syndrome characterized by a weakened immune system.

### Step 2: Identify the pathogen causing AIDS
AIDS is caused by the Human Immunodeficiency Virus (HIV).

**Hint:** Focus on the full form of HIV to understand its role in AIDS.

### Step 3: Recognize the type of virus HIV is
HIV is classified as a retrovirus. This means it has the ability to reverse transcribe its RNA into DNA using an enzyme called reverse transcriptase.

**Hint:** Retroviruses are unique because they can convert their RNA into DNA.

### Step 4: Understand the effect of HIV on the immune system
HIV specifically targets T-lymphocytes (T-cells), which are crucial for the immune response. By attacking these cells, HIV reduces the body’s immunity, leading to immunodeficiency.

**Hint:** T-lymphocytes are essential for a healthy immune system; their destruction leads to increased vulnerability to infections.

### Step 5: Analyze the statements provided in the options
1. **Viral RNA genome is converted into copied DNA by reverse transcriptase.** - This statement is correct.
2. **It is caused by retrovirus HIV.** - This statement is also correct.
3. **It is an immunodeficiency disease.** - This statement is correct as well.
4. **HIV selectively infects and kills B-lymphocytes.** - This statement is incorrect because HIV primarily attacks T-lymphocytes, not B-lymphocytes.

**Hint:** Compare each statement with the information you have gathered about HIV and AIDS.

### Step 6: Choose the incorrect statement
Based on the analysis, the incorrect statement is: **HIV selectively infects and kills B-lymphocytes.** This is false because HIV attacks T-lymphocytes.

**Final Answer:** The incorrect statement with respect to AIDS is option 4: "HIV selectively infects and kills B-lymphocytes."

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