Differentiate between rough and smooth endoplasmic reticulum. How is endoplasmic reticulum important for membrane biogenesis?

Explanation

The major differences between rough and smooth endoplasmic reticulum are
`{:("Smooth Endoplasmic Reticulum","Rough Endoplasmic Reticulum"),("SER has ribosomal particles on the","RER has particles of ribosome on the"),("surface hence look smooth.","surface therefore are rough in texture."),("It helps in manufacturing of lipids and fat molecules.","They are the sites of protein synthesis"):}`
Endoplasmic reticulum synthesises lipids (smooth endoplasic reticulum) and proteins (rough endoplasmic reticulum) which are responsible for formation of membrane. Thus, they help in membrane biogenesis.