Which of the following statements is not true about enzyme inhibitors ?

Options

A. inhibit the catalytic activity of the enzyme
B. Prevent the binding of substrate
C. Generally a strong covalent bond is formed between an inhibitor and an enzyme
D. Inhibitors can be competitive or non-competitive

Answer

C

Explanation

Drugs can block the binding site of the enzyme and present the binding of substrate or can inhibit the catalytic activity of the enzyme . Such durgs are called enzyme inhibitors. Durgs inhibit the attachment of substrate on active site of enzyme in two different ways.
(i) Durgs which compete with natural substrate for their attachement on the active sites of enzymes are cale competitive inhibitors.

(ii) However, some drugs do not bind to the active site but bind to a different site of anzyme i.e., allosteric site which changes the shape of the active site of the enzyme in such a way that the natural substrate cannot recogniz it. Such enzymes are called non-competitive inhibitors.
Generally, a weak bond such as hydrogen bonding, van der Waal's interactions etc, is formed between the enzyme and inhibtor.