Following pair of the organism are used for antibiotic production:

Options

A. Trichoderma and Monascus
B. Aspergillus niger and Penicillium notatum
C. Lactobacillus and Nucleopolyhedrovirus
D. Baculovirus and Streptococcus

Answer

To solve the question regarding which pair of organisms is used for antibiotic production, we can follow these steps:

### Step 1: Identify the Organisms
We need to analyze the organisms listed in the options provided. The question is asking for pairs of organisms that are known for their role in antibiotic production.

### Step 2: Evaluate Each Organism
- **Trichoderma**: This organism is primarily known for its role as a biocontrol agent against fungal pathogens. It does not produce antibiotics for human use.

- **Monascus**: This is a type of yeast that is known for its ability to lower cholesterol levels but is not recognized for antibiotic production.

- **Aspergillus niger**: This fungus is known for its ability to produce various enzymes and metabolites, including some antibiotics. It is often used in industrial applications but is not the primary source of the most well-known antibiotics.

- **Penicillium notatum**: This is a well-known source of penicillin, the first antibiotic discovered, which is widely used to treat bacterial infections.

### Step 3: Identify the Correct Pair
From the analysis:
- **Aspergillus niger** does contribute to antibiotic production, but it is not as prominent as **Penicillium notatum**.
- **Penicillium notatum** is a classic example of an organism used for antibiotic production.

Thus, the correct pair of organisms used for antibiotic production is **Aspergillus niger and Penicillium notatum**.

### Final Answer
The pair of organisms used for antibiotic production is **Aspergillus niger and Penicillium notatum**.

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