In a typical antibody, disulphide bonds are not seen in which of the following?

Options

A. between heavy chain and light chain
B. between two heavy chains
C. between two light chains
D. within the heavy chain

Answer

To solve the question regarding the presence of disulfide bonds in a typical antibody, we will analyze the structure of antibodies and the locations of disulfide bonds.

### Step-by-Step Solution:

1. **Understanding Antibody Structure**:
- Antibodies are Y-shaped molecules composed of four polypeptide chains: two heavy chains and two light chains.
- The heavy chains are usually longer and have more complex structures than the light chains.

2. **Identifying Disulfide Bonds**:
- Disulfide bonds (S-S bonds) are covalent bonds that form between the sulfur atoms of cysteine residues.
- In antibodies, disulfide bonds are crucial for maintaining the structural integrity of the molecule.

3. **Analyzing the Options**:
- **Option 1**: Disulfide bond between heavy chain and light chain.
- Disulfide bonds are present between the heavy and light chains to stabilize the structure.
- **Option 2**: Disulfide bond between two heavy chains.
- Disulfide bonds are also present between the two heavy chains, linking them together.
- **Option 3**: Disulfide bond between two light chains.
- In a typical antibody structure, there are no disulfide bonds between the two light chains. They do not form direct disulfide linkages with each other.
- **Option 4**: Disulfide bond within heavy chains.
- Disulfide bonds are present within the heavy chains, contributing to their stability.

4. **Conclusion**:
- The only option where disulfide bonds are not found is between the two light chains. Therefore, the correct answer is the option that states disulfide bonds are not present between two light chains.

### Final Answer:
Disulfide bonds are not seen between two light chains in a typical antibody.

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