Which of the following is incorrect about cancer ?

Options

A. Metastasis is seen only in the case of a malignant tumor.
B. The activation of c-onc genes leads to development of tumors.
C. The patient are given substances called biological response modifiers such as alpha-interferons which activates their immune system and helps in destroying the tumor.
D. None of the above

Answer

To determine which statement about cancer is incorrect, we will analyze each option provided in the question.

1. **Metastasis is seen only in the case of malignant tumors.**
- This statement is **correct**. Metastasis refers to the spread of cancer cells from the primary tumor to other parts of the body, and this phenomenon is characteristic of malignant tumors. Benign tumors do not metastasize.

2. **The activation of the c-onc genes leads to the development of tumors.**
- This statement is also **correct**. The c-onc genes (proto-oncogenes) can become activated through mutations, leading to uncontrolled cell proliferation and tumor development.

3. **Patients are given substances called biological response modifiers such as alpha interferons which activate their immune system and help in destroying the tumor.**
- This statement is **correct** as well. Biological response modifiers like alpha interferons are used in cancer treatment to enhance the immune response against tumors.

4. **None of the above.**
- This option suggests that all previous statements are correct.

After analyzing all the statements, we find that all the statements provided are correct. Therefore, the answer to the question "Which of the following is incorrect about cancer?" is:

**Correct Answer: Option 4 - None of the above.**