If a sequence of non-template strand is 5'-ATGTGACGAG-3', the sequence of anticodon on tRNA will be

Options

A. AUGUGACGAG
B. UACACUGCUC
C. ATGTGACGAG
D. AUGUGTCCTA

Answer

To determine the sequence of the anticodon on tRNA based on the given non-template strand of DNA, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Non-Template Strand**: The given sequence is 5'-ATGTGACGAG-3'. This is the non-template strand of DNA.

2. **Transcribe to mRNA**: The non-template strand is similar to the mRNA sequence, except that thymine (T) in DNA is replaced by uracil (U) in RNA. Therefore, we will convert the DNA sequence to mRNA:
- A → A
- T → U
- G → G
- T → U
- G → G
- A → A
- C → C
- G → G
- A → A
- G → G

Thus, the mRNA sequence is 5'-AUGUGACGAG-3'.

3. **Determine the Anticodon**: The anticodon on tRNA is complementary to the mRNA codons and is also written in the 5' to 3' direction. To find the anticodon, we will pair the mRNA sequence:
- A → U
- U → A
- G → C
- U → A
- G → C
- A → U
- C → G
- G → C
- A → U
- G → C

Therefore, the anticodon sequence will be:
- 3'-UACACUGCUC-5'

4. **Write the Anticodon in 5' to 3' Direction**: Since anticodons are conventionally written in the 5' to 3' direction, we reverse the sequence:
- 5'-CUGCUGUAC-3'

### Final Answer:
The sequence of the anticodon on tRNA is **5'-CUGCUGUAC-3'**.

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