Which of the following will produce adenosine triphosphate by substrate - level phosphorylation ?

Options

A. 2 - phoshoglycerate to 2 - phosphoenol pyruvate
B. Glucose to Glucose - 6 - phosphate
C. Phosphoenol pyruvic acid to pyruvic acid
D. Frutose 1 , 6 - biphosphate to PGAL and DHAP C

Answer

To solve the question regarding which process produces adenosine triphosphate (ATP) by substrate-level phosphorylation, we will analyze the options provided in the context of glycolysis, where substrate-level phosphorylation occurs.

### Step-by-Step Solution:

1. **Understanding Substrate-Level Phosphorylation**:
- Substrate-level phosphorylation is a process where a phosphate group is directly transferred from a substrate molecule to ADP, forming ATP. This occurs in specific steps during glycolysis and the citric acid cycle.

2. **Analyzing the Options**:
- **Option 1**: 2-phosphoglycerate to 2-phosphoenolpyruvate
- This step involves the removal of a water molecule and does not produce ATP.
- **Option 2**: Glucose to glucose 6-phosphate
- This step involves the conversion of glucose to glucose 6-phosphate using ATP, but it does not produce ATP.
- **Option 3**: Phosphoenolpyruvic acid to pyruvic acid
- In this step, ADP is phosphorylated to form ATP. This is a classic example of substrate-level phosphorylation occurring during glycolysis.
- **Option 4**: Fructose 1,6-bisphosphate to PGAL-DHAP
- This step involves the conversion of fructose 1,6-bisphosphate into two triose phosphates (PGAL and DHAP) and does not produce ATP.

3. **Conclusion**:
- The only option that results in the production of ATP through substrate-level phosphorylation is **Option 3: Phosphoenolpyruvic acid to pyruvic acid**.

### Final Answer:
The correct answer is **Option 3: Phosphoenolpyruvic acid to pyruvic acid**.