I. ER divide the intracellular space into two distinct compartments.
II. SER is a major site for the synthesis of lipids.
III. ER is also called the control center of the cell.
IV. The ER modified chemicals that are toxin to the cell.
V. The ER with ribosomes in their surface is called RER.
Which of the following statements is /are about the ER ?

Options

A. None
B. All except III , IV
C. All except III
D. All

Answer

To solve the question regarding the statements about the endoplasmic reticulum (ER), we will analyze each statement one by one:

### Step-by-Step Solution:

1. **Statement I: "ER divides the intracellular space into two distinct compartments."**
- This statement is **correct**. The endoplasmic reticulum (ER) indeed divides the intracellular space into two compartments: the luminal compartment (inside the ER) and the extraluminal compartment (the cytosol).

2. **Statement II: "SER is a major site for the synthesis of lipids."**
- This statement is also **correct**. The smooth endoplasmic reticulum (SER) is primarily responsible for lipid synthesis, including phospholipids and cholesterol.

3. **Statement III: "ER is also called the control center of the cell."**
- This statement is **incorrect**. The control center of the cell is the nucleus, not the endoplasmic reticulum. The ER plays a role in cellular functions but does not control them.

4. **Statement IV: "The ER modifies chemicals that are toxic to the cell."**
- This statement is **correct**. The ER, particularly the smooth ER, is involved in detoxifying harmful metabolic byproducts and drugs.

5. **Statement V: "The ER with ribosomes on their surface is called RER."**
- This statement is **correct**. The rough endoplasmic reticulum (RER) is characterized by the presence of ribosomes on its surface, which are involved in protein synthesis.

### Summary of Statements:
- **Correct Statements**: I, II, IV, V
- **Incorrect Statement**: III

### Conclusion:
The statements about the endoplasmic reticulum are as follows:
- I, II, IV, and V are correct.
- III is incorrect.

### Answer:
The correct option is that all statements are correct except for the third statement.

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