Replication in E.coli DNA starts in a definite region known as

Options

A. Promoter region
B. Origin of replication
C. Replication fork
D. Template strand

Answer

To solve the question "Replication in E.coli DNA starts in a definite region known as", we will analyze the options provided and identify the correct answer step by step.

### Step 1: Understand the Question
The question is asking for the specific region in the DNA of E.coli where replication begins. This is a fundamental concept in molecular biology, particularly in the study of prokaryotic DNA replication.

### Step 2: Analyze the Options
1. **Promoter Region**: This is a sequence of DNA where RNA polymerase binds to initiate transcription. It is not involved in DNA replication. Therefore, this option is incorrect.

2. **Origin of Replication**: This is the specific location on the DNA where replication begins. In E.coli, this is a well-defined region known as "oriC". This option is correct.

3. **Replication Fork**: This structure forms during the process of DNA replication as the DNA unwinds. It is not a starting point for replication but rather a structure that develops as replication progresses. Thus, this option is incorrect.

4. **Template Strand**: This refers to the strand of DNA that is used as a template for synthesizing a new strand during replication. It is not a specific starting point for replication. Therefore, this option is also incorrect.

### Step 3: Conclusion
Based on the analysis of the options, the correct answer to the question is **"Origin of Replication"**.

### Final Answer
**The replication in E.coli DNA starts in a definite region known as the Origin of Replication.**

---