Which of these symptoms is caused by the entry of sporozoites ?

Options

A. Oedema (swelling) and thickening of skin and underlying tissues especially in the legs and genitals .
B. Characteristics fever causing a feeling of cold, chills and rigor followed by increase in temperature and finally causing profuse sweating
C. Vomiting, indigestion and diarrhea, gastrointestinal pain and discomfort
D. Abscess in the liver

Answer

To solve the question regarding which symptom is caused by the entry of sporozoites, we can analyze each option provided:

### Step-by-Step Solution:

1. **Understanding Sporozoites**:
- Sporozoites are the infective stage of certain protozoan parasites, such as Plasmodium, which causes malaria. They are transmitted to humans through the bite of infected female Anopheles mosquitoes.

2. **Analyzing the Options**:
- **Option 1: Oedema**:
- Oedema refers to swelling due to fluid accumulation in tissues. This is typically associated with filariasis, not sporozoite entry. Therefore, this option is incorrect.

- **Option 2: Characteristic fever with chills and sweating**:
- This symptom is indicative of malaria. When sporozoites enter the bloodstream, they infect liver cells, leading to the release of merozoites that cause cyclical fevers, chills, and sweating. This option is correct.

- **Option 3: Vomiting, indigestion, diarrhea**:
- These symptoms are more aligned with gastrointestinal infections, such as typhoid fever. They are not caused by sporozoites. Thus, this option is incorrect.

- **Option 4: Abscess on the liver**:
- While liver abscesses can occur due to various infections, they are not a direct symptom of sporozoite entry. This option is also incorrect.

3. **Conclusion**:
- The only symptom that is directly caused by the entry of sporozoites is the characteristic fever with chills and profuse sweating. Therefore, the correct answer is **Option 2**.

### Final Answer:
**The symptom caused by the entry of sporozoites is: Characteristic fever causing a feeling of cold chills and rigors followed by an increase in temperature and finally causing profuse sweating.**

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