Select the correct statement regarding okazaki fragments formed during DNA replication

Options

A. They are the short DNA fragments on the lagging strand.
B. They are the short DNA fragments on the leading strand
C. They are the RNA primers required for initiation of DNA synthesis.
D. They are the fragments of DNA produced by Danes.

Answer

To solve the question regarding Okazaki fragments formed during DNA replication, let's analyze the statements provided and determine which one is correct.

### Step-by-Step Solution:

1. **Understanding Okazaki Fragments**:
- Okazaki fragments are short segments of DNA that are synthesized on the lagging strand during DNA replication. This occurs because DNA synthesis can only proceed in the 5' to 3' direction.

**Hint**: Remember that DNA replication is semi-discontinuous, meaning one strand (leading) is synthesized continuously while the other (lagging) is synthesized in short fragments.

2. **Analyzing the Statements**:
- **Statement 1**: "They are the short DNA fragments on the lagging strand."
- This statement is true. Okazaki fragments are indeed formed on the lagging strand.

- **Statement 2**: "They are the short DNA fragments on the leading strand."
- This statement is false. The leading strand is synthesized continuously without the formation of Okazaki fragments.

- **Statement 3**: "They are the RNA primers required for initiation of DNA synthesis."
- This statement is false. RNA primers are not Okazaki fragments; they are short RNA sequences that initiate DNA synthesis.

- **Statement 4**: "They are the fragments of DNA produced by Dens."
- This statement is misleading and false. The term "Dens" does not refer to any known process or enzyme related to Okazaki fragments.

3. **Conclusion**:
- The correct statement regarding Okazaki fragments is the first one: "They are the short DNA fragments on the lagging strand."

### Final Answer:
The correct statement regarding Okazaki fragments formed during DNA replication is: **They are the short DNA fragments on the lagging strand.**