Identify the biocatalyst that helps in obtaining the connecting link between glycolysis and Kreb's cycle .

Options

A. Pyruvate carboxylase
B. Malate dehydrogenase
C. Pyruvate dehydrogenase
D. Acetyl CoA dehydrogenase

Answer

To solve the question of identifying the biocatalyst that helps in obtaining the connecting link between glycolysis and the Krebs cycle, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Glycolysis**:
- Glycolysis is the first step of cellular respiration that occurs in both aerobic and anaerobic organisms. It takes place in the cytoplasm and does not require oxygen.
- The main product of glycolysis is pyruvate.

2. **Identify the Product of Glycolysis**:
- The end product of glycolysis is pyruvate (or pyruvic acid).

3. **Link Between Glycolysis and the Krebs Cycle**:
- Pyruvate produced in glycolysis is not directly used in the Krebs cycle. Instead, it undergoes further processing to form a new compound that can enter the Krebs cycle.

4. **Conversion of Pyruvate**:
- Pyruvate is oxidized to form Acetyl-CoA (Acetyl coenzyme A). This process involves the removal of a carbon atom from pyruvate, which is released as carbon dioxide (CO2).

5. **Identify the Biocatalyst**:
- The enzyme that catalyzes the conversion of pyruvate to Acetyl-CoA is known as **Pyruvate Dehydrogenase**. This enzyme plays a crucial role in linking glycolysis to the Krebs cycle.

6. **Conclusion**:
- Therefore, the biocatalyst that helps in obtaining the connecting link between glycolysis and the Krebs cycle is **Pyruvate Dehydrogenase**.

### Final Answer:
**Pyruvate Dehydrogenase**

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