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In a DNA molecule, nitrogenous base is l...

In a DNA molecule, nitrogenous base is linked to pentose sugar by 'A' linkage and the pentose sugar is linked to phosphate by 'B' linkage. Correctly identify A and B.

A

`{:("Column A ","Column B"),("N - Glycoside linkage","Amide linkage"):}`

B

`{:("Column A ","Column B"),("N - Glycoside linkage","Phosphodiester linkage"):}`

C

`{:("Column A ","Column B"),("Phosphodiester linkage","Phosphodiester linkage"):}`

D

`{:("Column A ","Column B"),("Amide linkage","Phosphodiester linkage"):}`

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AI Generated Solution

The correct Answer is:
To solve the question regarding the linkages in a DNA molecule, we need to identify the types of bonds that connect the nitrogenous base to the pentose sugar and the pentose sugar to the phosphate group. ### Step-by-Step Solution 1. **Understanding the Structure of DNA**: - DNA is made up of nucleotides, which consist of a nitrogenous base, a pentose sugar (deoxyribose), and a phosphate group. 2. **Identifying the Linkage between Nitrogenous Base and Pentose Sugar**: - The nitrogenous base is attached to the first carbon of the pentose sugar. The type of bond that forms between the nitrogenous base and the sugar is known as a **glycosidic bond**. This bond is formed through a condensation reaction where a water molecule is removed. 3. **Identifying the Linkage between Pentose Sugar and Phosphate Group**: - The phosphate group is attached to the fifth carbon of the pentose sugar. The bond that forms between the sugar and the phosphate group is called a **phosphodiester bond**. This bond is formed between the hydroxyl group of the sugar and the phosphate group, also through a condensation reaction. 4. **Conclusion**: - Therefore, we can conclude that: - **A (linkage between nitrogenous base and pentose sugar)** is **glycosidic linkage**. - **B (linkage between pentose sugar and phosphate)** is **phosphodiester linkage**. ### Final Answer: - A = Glycosidic linkage - B = Phosphodiester linkage
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