Which one of the following conditions indicates Klinefeter's syndrome ?

Options

A. 44 + XXY
B. 44 + XO
C. 44 + XY
D. 44 + XX

Answer

To solve the question regarding which condition indicates Klinefelter's syndrome, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Klinefelter's Syndrome**:
- Klinefelter's syndrome is a chromosomal disorder that occurs in males due to the presence of an extra X chromosome.

2. **Chromosomal Composition**:
- Normally, males have one X and one Y chromosome (XY). In Klinefelter's syndrome, there is an additional X chromosome, resulting in a karyotype of XXY.

3. **Identifying the Karyotype**:
- The karyotype for Klinefelter's syndrome is XXY, which means there are a total of 47 chromosomes (44 autosomes + 3 sex chromosomes: XXY).

4. **Evaluating the Options**:
- The options provided in the question are:
1. 44 + XY (normal male)
2. 44 + XX (normal female)
3. 44 + XXY (Klinefelter's syndrome)
4. 44 + XO (Turner syndrome)
- Among these, the option that indicates Klinefelter's syndrome is 44 + XXY.

5. **Conclusion**:
- Therefore, the correct answer is option 3: 44 + XXY.