Menstrual cycle is ceased during pregnancy is due to negative feedback of :

Options

A. FSH
B. ADN
C. Oxytocin
D. Progesterone

Answer

To solve the question regarding why the menstrual cycle ceases during pregnancy due to negative feedback, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Menstrual Cycle**:
- The menstrual cycle is regulated by hormones, primarily estrogen and progesterone, which are produced by the ovaries. The cycle involves the preparation of the uterus for potential pregnancy.

2. **Role of Hormones in Pregnancy**:
- During pregnancy, the body undergoes significant hormonal changes. The presence of a fertilized egg triggers the production of certain hormones to maintain the pregnancy.

3. **Identifying the Hormones**:
- The key hormones involved in the menstrual cycle are:
- Follicle Stimulating Hormone (FSH)
- Luteinizing Hormone (LH)
- Estrogen
- Progesterone
- Oxytocin (not directly involved in menstrual cycle regulation)

4. **Negative Feedback Mechanism**:
- In a normal menstrual cycle, FSH and LH stimulate the ovaries to produce estrogen and progesterone. When pregnancy occurs, the developing placenta produces human chorionic gonadotropin (hCG), which maintains the corpus luteum, leading to continued production of progesterone.

5. **Effect of Progesterone**:
- Progesterone plays a crucial role in maintaining the uterine lining and preventing further ovulation. It exerts a negative feedback effect on the hypothalamus and pituitary gland, inhibiting the release of FSH and LH, thus stopping the menstrual cycle.

6. **Conclusion**:
- Therefore, the cessation of the menstrual cycle during pregnancy is primarily due to the negative feedback effect of **progesterone**.

### Final Answer:
The menstrual cycle is ceased during pregnancy due to the negative feedback of **progesterone**.

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