Which of the following will occur in the vertebrae host with respect to plasmodium ?
(a) Formation of the motile zygote
(b) Maturation of gametocytes (c) Formation of Sporozoites
(d) Release of homozoin
(e) Recurrent fever

Options

A. a,c,d
B. a,b,c,d,e
C. b,d and e
D. d and e only

Answer

To solve the question regarding what occurs in the vertebrate host with respect to Plasmodium, we need to analyze each option provided:

1. **Formation of the motile zygote**: This occurs in the mosquito gut, not in the vertebrate host (human). Therefore, this option is incorrect.

2. **Maturation of gametocytes**: The maturation of gametocytes also takes place in the mosquito, specifically in the midgut lumen. Hence, this option is incorrect as well.

3. **Formation of Sporozoites**: Sporozoites are formed in the salivary glands of the mosquito, not in the vertebrate host. Thus, this option is incorrect.

4. **Release of hemozoin**: Hemozoin is a byproduct of the digestion of hemoglobin by the Plasmodium parasite in the red blood cells of the vertebrate host. This process does occur in humans, making this option correct.

5. **Recurrent fever**: This is a symptom experienced by humans infected with Plasmodium due to the cyclical release of merozoites from red blood cells, leading to febrile episodes. Therefore, this option is also correct.

Based on the analysis, the correct answers are:
- **Release of hemozoin (D)**
- **Recurrent fever (E)**

Thus, the final answer is **D and E only**.