Select the odd out with respect to increased of decreased secretion of hormones .

Options

A. Diabetes mellitus
B. Grave's disease
C. Cretinism
D. Addison's disease

Answer

To solve the question of selecting the odd one out with respect to increased or decreased secretion of hormones, we will analyze each of the diseases mentioned in the question: Diabetes mellitus, Graves' disease, Creatinism, and Addison's disease.

### Step-by-Step Solution:

1. **Diabetes Mellitus**:
- **Hormone Involved**: Insulin
- **Secretion**: Decreased secretion of insulin from the pancreas.
- **Effect**: Leads to increased blood glucose levels.

2. **Graves' Disease**:
- **Hormone Involved**: Thyroid hormones (T3 and T4)
- **Secretion**: Increased secretion of thyroid hormones.
- **Effect**: Causes hyperthyroidism, leading to an increased metabolic rate and enlarged thyroid gland.

3. **Creatinism**:
- **Hormone Involved**: Thyroid hormones (T3 and T4)
- **Secretion**: Decreased secretion of thyroid hormones.
- **Effect**: Results in hypothyroidism, leading to poor growth and development, especially in children.

4. **Addison's Disease**:
- **Hormone Involved**: Adrenal cortex hormones (like cortisol)
- **Secretion**: Decreased secretion of adrenal hormones.
- **Effect**: Results in symptoms like fatigue, weight loss, and low blood pressure.

### Conclusion:
- **Odd One Out**: **Graves' Disease** is the odd one out because it is characterized by **increased secretion** of hormones, while the other three diseases (Diabetes Mellitus, Creatinism, and Addison's Disease) are associated with **decreased secretion** of hormones.