Select the incorrect statement with respect to mitotic anaphase .

Options

A. Chromatids of the chromosome at the metaphase plate are split simultaneously .
B. The centromere of each chromosomes remains directed towards the pole as the chromosome moves away .
C. Chromosomes cluster at the opposite poles and their identity is lost as discrete elements.
D. It is the best stage to study the position of the centromere in the chromosomes .

Answer

To determine the incorrect statement regarding mitotic anaphase, we need to analyze the key events that occur during this phase of mitosis.

### Step-by-Step Solution:

1. **Understanding Mitosis**: Mitosis is a type of cell division that results in two daughter cells with the same number of chromosomes as the parent cell. It consists of several stages: prophase, metaphase, anaphase, and telophase.

2. **Focus on Anaphase**: During anaphase, the key events include:
- The splitting of the centromeres that hold sister chromatids together.
- The separation of sister chromatids, which are then pulled towards opposite poles of the cell by spindle fibers.

3. **Analyzing Statements**: We are given several statements about anaphase and need to identify which one is incorrect:
- **Statement A**: "The chromatids of the chromosomes are split on the metaphase plate."
- This is incorrect because chromatids are split during anaphase, not on the metaphase plate.
- **Statement B**: "The centromere of each chromosome is directed towards the pole as the chromosome moves."
- This is correct; as chromatids move, their centromeres lead towards the poles.
- **Statement C**: "Chromosomes get clustered on opposite poles and discrete elements get lost."
- This is also correct; once the chromatids reach the poles, they cluster there.
- **Statement D**: "The centromere's position is the best time to study chromosomes."
- This statement is incorrect because the best stage to observe chromosomes is metaphase, not anaphase.

4. **Conclusion**: The incorrect statement regarding mitotic anaphase is **Statement A**.

### Final Answer:
The incorrect statement with respect to mitotic anaphase is: **"The chromatids of the chromosomes are split on the metaphase plate."**