Which of the following organism does not follow the central dogma of molecular biology ?

Options

A. Mucor
B. Chlamydomonas
C. Bacteria
D. HIV

Answer

To determine which organism does not follow the central dogma of molecular biology, we need to first understand what the central dogma entails. The central dogma describes the flow of genetic information within a biological system, typically summarized as:

1. **DNA → RNA → Protein**
- **Transcription**: The process by which DNA is transcribed into RNA.
- **Translation**: The process by which RNA is translated into protein.
- **Replication**: The process by which DNA is copied to produce more DNA.

Now, let's analyze the options provided:

A. **Muscle**: Muscle cells, like all eukaryotic cells, follow the central dogma. They transcribe DNA to RNA and then translate RNA to proteins.

B. **Chlamydomonas**: This is a type of green algae, which is also a eukaryote. It follows the central dogma as well.

C. **Bacteria**: Bacteria are prokaryotic organisms that also follow the central dogma, where they transcribe DNA to RNA and then translate RNA to proteins.

D. **HIV**: HIV (Human Immunodeficiency Virus) is a retrovirus. Retroviruses have RNA as their genetic material. They do not follow the central dogma in the traditional sense because they reverse the flow of information. Specifically, HIV uses an enzyme called reverse transcriptase to convert its RNA into DNA. This DNA can then be integrated into the host's genome and subsequently transcribed into RNA, which is then translated into proteins.

Based on this analysis, the organism that does not follow the central dogma of molecular biology is:

**Answer: D. HIV**