Select the CORRECT statement from the following.

Options

A. During mitosis, endoplasmic reticulum and nucleolus disappear completely at early prophase
B. Chromosomes are arranged along the equator during prophase
C. Chromosomes is made up of two sister chromatids at anaphase of mitosis .
D. A cell plate is laid down during interphase

Answer

To solve the question of selecting the correct statement from the provided options, we will analyze each statement step by step:

### Step 1: Analyze the First Statement
**Statement:** During mitosis, endoplasmic reticulum and nucleolus disappears completely at the early prophase.

**Analysis:** This statement is incorrect. The endoplasmic reticulum and nucleolus do not disappear completely until late prophase. Therefore, this statement is false.

### Step 2: Analyze the Second Statement
**Statement:** Chromosomes are arranged along the equator during the prophase.

**Analysis:** This statement is also incorrect. Chromosomes align along the equatorial plane during metaphase, not prophase. Hence, this statement is false.

### Step 3: Analyze the Third Statement
**Statement:** Chromosome is made up of two sister chromatids at the anaphase of mitosis.

**Analysis:** This statement is correct. During anaphase, the sister chromatids are separated and pulled towards opposite poles of the cell, and each chromatid is considered a chromosome. Thus, this statement is true.

### Step 4: Analyze the Fourth Statement
**Statement:** A cell plate is laid down during the interphase.

**Analysis:** This statement is incorrect. The cell plate is formed during telophase, not interphase. Therefore, this statement is false.

### Conclusion
After analyzing all the statements, the only correct statement is the third one: "Chromosome is made up of two sister chromatids at the anaphase of mitosis."

### Final Answer
The correct statement is: **"Chromosome is made up of two sister chromatids at the anaphase of mitosis."**

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