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The frequency of two alleles in a gene p...

The frequency of two alleles in a gene pool is 0.19 (A) and 0.8 (a) . Assume that the population is in Hardy-Weinberg equilibrium and
(a) Calculate the percentage of heterozygous individuals in the population.
(b) Calculate the percentage of homozygous recessive in the population .

A

`60% and 40%`

B

`66% and 31%`

C

`40% and 60%`

D

`31% and 66%`

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The correct Answer is:
To solve the problem, we will use the Hardy-Weinberg principle, which provides a mathematical model to study genetic variation in a population at equilibrium. ### Step-by-Step Solution: **Step 1: Identify Allele Frequencies** - We are given the frequencies of two alleles: - Frequency of allele A (p) = 0.19 - Frequency of allele a (q) = 0.8 **Step 2: Verify the Allele Frequencies** - According to Hardy-Weinberg equilibrium, the sum of the allele frequencies must equal 1. - p + q = 0.19 + 0.8 = 0.99 - Since the sum is not equal to 1, we need to adjust the frequencies. Let's assume the frequency of allele a is actually 0.81 (which is a common mistake in transcription). Thus: - p = 0.19 - q = 0.81 **Step 3: Calculate the Percentage of Heterozygous Individuals** - The formula for the frequency of heterozygous individuals (2pq) is: - 2pq = 2 * p * q - Substituting the values: - 2 * 0.19 * 0.81 = 0.3078 - To convert this to a percentage: - 0.3078 * 100 = 30.78% **Step 4: Calculate the Percentage of Homozygous Recessive Individuals** - The formula for the frequency of homozygous recessive individuals (q²) is: - q² = (0.81)² - Calculating this: - (0.81)² = 0.6561 - To convert this to a percentage: - 0.6561 * 100 = 65.61% ### Final Answers: (a) Percentage of heterozygous individuals = 30.78% (b) Percentage of homozygous recessive individuals = 65.61%
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