Co- factor and prosthetic groups are ………... compounds, …………... bound to apoenzyme.

Options

A. organic, transiently
B. inorganic, tightly
C. organic, tightly
D. inorganic, transiently

Answer

To solve the question, we need to fill in the blanks regarding the nature of cofactors and prosthetic groups and how they bind to the apoenzyme.

### Step-by-Step Solution:

1. **Understanding Cofactors and Prosthetic Groups**:
- Cofactors are non-protein molecules that assist enzymes in catalyzing reactions. They can be either organic or inorganic.
- Prosthetic groups are a specific type of cofactor that are tightly bound to the enzyme.

2. **Identifying the Nature of Cofactors and Prosthetic Groups**:
- Both cofactors and prosthetic groups are typically organic compounds. This means they contain carbon and are derived from living organisms.

3. **Understanding Binding to Apoenzyme**:
- An apoenzyme is the protein part of an enzyme, which requires a cofactor or prosthetic group to become active.
- Prosthetic groups are tightly bound to the apoenzyme, meaning they are not easily removed and are integral to the enzyme's structure and function.

4. **Filling in the Blanks**:
- The first blank should be filled with "organic" to describe the nature of cofactors and prosthetic groups.
- The second blank should be filled with "tightly" to describe how prosthetic groups bind to the apoenzyme.

5. **Final Answer**:
- Cofactor and prosthetic groups are **organic** compounds, **tightly** bound to apoenzyme.