Select the incorrect statement from the following.

Options

A. The HGP was a 13 year project.
B. The fragments of DNA were sequenced using automated DNA sequence that worked on the principle developed by sanger
C. The sequence of chromosome 1 was completed in May 2003.
D. Less than 2% of the genome codes for protein .

Answer

To solve the question of selecting the incorrect statement from the provided options, we will evaluate each statement one by one.

### Step-by-Step Solution:

1. **Evaluate Statement 1**: "The HGP was a 13-year project."
- The Human Genome Project (HGP) indeed lasted from 1990 to 2003, which totals 13 years.
- **Conclusion**: This statement is **correct**.

2. **Evaluate Statement 2**: "The fragments of DNA were sequenced using automated DNA sequencers that were worked on the principle developed by Sanger."
- Sanger sequencing is a well-known method for DNA sequencing, and it has been partially automated in modern sequencing technologies.
- **Conclusion**: This statement is **correct**.

3. **Evaluate Statement 3**: "The sequence of chromosome 1 was completed in May 2003."
- The sequencing of chromosome 1 was indeed a significant milestone in the Human Genome Project, but it was not completed in May 2003. The entire project was completed in April 2003, and while chromosome 1 was sequenced, it was not the last chromosome to be completed.
- **Conclusion**: This statement is **incorrect**.

4. **Evaluate Statement 4**: "Less than 2% of the genome codes for protein."
- It is widely accepted that approximately 1-2% of the human genome actually codes for proteins, while the rest includes regulatory sequences and non-coding DNA.
- **Conclusion**: This statement is **correct**.

### Final Answer:
The incorrect statement among the options provided is **Statement 3**: "The sequence of chromosome 1 was completed in May 2003."