Which of the following events are not associated with the phase /cycle of malarial parasite in man ?

Options

A. Entry of parasite into hepatocytes
B. Formation of motile zygote
C. Formation of gametocytes
D. Erythrocytic schizogony

Answer

To determine which event is not associated with the life cycle of the malarial parasite in humans, we need to analyze each option provided.

### Step-by-Step Solution:

1. **Understanding the Life Cycle of Malarial Parasite**:
- The malarial parasite, primarily *Plasmodium*, has a complex life cycle that involves both humans and female *Anopheles* mosquitoes. The cycle includes asexual reproduction in humans and sexual reproduction in mosquitoes.

2. **Analyzing Each Option**:
- **Entry of Parasite into Hepatocytes**: This is the first step after the mosquito injects the sporozoites into the human bloodstream. The sporozoites travel to the liver and invade hepatocytes (liver cells) to multiply. This event is associated with the life cycle.

- **Formation of Motile Zygote**: This is incorrect in the context of the human phase of the life cycle. Zygotes are formed in the mosquito's gut after fertilization of gametes, and they are not motile. Therefore, this event does not occur in humans.

- **Formation of Gametocytes**: This occurs in the human host. After asexual reproduction in red blood cells, some parasites differentiate into gametocytes, which are then taken up by the mosquito. This event is associated with the life cycle.

- **Erythrocytes Schizogony**: This refers to the asexual reproduction of the parasite within red blood cells (erythrocytes), leading to the rupture of these cells and the release of new merozoites. This event is also associated with the life cycle.

3. **Conclusion**:
- The event that is **not associated** with the phase/cycle of the malarial parasite in humans is the **Formation of Motile Zygote**.

### Final Answer:
The event that is not associated with the phase/cycle of the malarial parasite in humans is the **Formation of Motile Zygote**.

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