Read the following statement and select the incorrect one amongst the following.

Options

A. `T_4` is the chief circulating form of throid hormone, but is less active than `T_3`
B. Acromegaly is usually associated with hypoglycemia and hypotension
C. Thyroxine promotes the body growth and metamorphosis in amphibians
D. Hypothalamus produces the hormone concerned with milk ejection.

Answer

To solve the question, we need to analyze each statement provided and identify which one is incorrect.

### Step-by-Step Solution:

1. **Statement Analysis**:
- **Statement 1**: "T4 is a chief circulating form of the thyroid hormone but is less active than T3."
- This statement is **correct**. T4 (Thyroxine) is indeed the primary form of thyroid hormone in circulation, but T3 (Triiodothyronine) is more biologically active.

2. **Statement 2**: "Acromegaly is usually associated with hypoglycemia and hypotension."
- This statement is **incorrect**. Acromegaly is characterized by excessive growth hormone production, which typically leads to hyperglycemia (high blood sugar) rather than hypoglycemia (low blood sugar). It is also not associated with hypotension (low blood pressure); rather, it can lead to hypertension (high blood pressure).

3. **Statement 3**: "Thyroxine promotes body growth and metamorphosis in amphibians."
- This statement is **correct**. Thyroxine plays a crucial role in regulating growth and metamorphosis in amphibians.

4. **Statement 4**: "Hypothalamus produces the hormone that is concerned with milk ejection."
- This statement is **correct**. The hypothalamus produces oxytocin, which is responsible for milk ejection during breastfeeding.

### Conclusion:
The incorrect statement among the options is **Statement 2**: "Acromegaly is usually associated with hypoglycemia and hypotension."