Which of the following statements is not Correct ?

Options

A. Brunner's glands are present in the submucosa of stomach and secrete pepsinogen
B. Goblet cells are present in the mucosa of intestine and secrete HCL
C. Oxyntic cells are present in the mucosa of stomach and secrete HCL
D. Acini are present in the pancreas and secrete carboxypeptidase

Answer

To determine which statement is not correct, let's analyze each of the statements provided:

1. **Brunner's glands are present in the submucosa of the stomach and secrete pepsinogen.**
- This statement is incorrect. Brunner's glands are actually located in the submucosa of the duodenum, not the stomach. They secrete alkaline mucus to neutralize gastric acid and provide an optimal environment for intestinal enzymes. Pepsinogen is secreted by gastric chief cells in the stomach, not by Brunner's glands.

2. **Brunner's glands are present in the submucosa of the duodenum.**
- This statement is correct. Brunner's glands are indeed located in the submucosa of the duodenum.

3. **Brunner's glands protect our stomach from acidic medium.**
- This statement is misleading. While Brunner's glands do help to neutralize the acidic content coming from the stomach, they are not located in the stomach itself. Their primary function is in the duodenum.

4. **Brunner's glands provide an alkaline medium.**
- This statement is correct. Brunner's glands secrete alkaline mucus which helps to neutralize gastric acid.

5. **Goblet cells are present in the mucous of intestine and secrete HCl.**
- This statement is incorrect. Goblet cells are found in the intestinal lining and secrete mucus, not hydrochloric acid (HCl). HCl is secreted by parietal cells in the stomach.

6. **Oxyntic cells are present in the mucosa of the stomach and secrete HCl.**
- This statement is correct. Oxyntic cells (or parietal cells) are indeed found in the stomach and secrete hydrochloric acid.

7. **Acini are present in the pancreas and secrete carboxypeptidase.**
- This statement is correct. Acini are clusters of cells in the pancreas that secrete digestive enzymes, including carboxypeptidase.

**Conclusion:**
The statements that are not correct are:
- "Brunner's glands are present in the submucosa of the stomach and secrete pepsinogen."
- "Goblet cells are present in the mucous of intestine and secrete HCl."

**Final Answer:**
The first statement is the one that is not correct.

---