If progesterone receptors are disrupted then

Options

A. Secondary sexual characters would not be maintained.
B. pituitary gonadotropins will not be secreted.
C. the uterus will not be able to support pregnancy.
D. the uterine endometrium will not begin to proliferate.

Answer

To solve the question "If progesterone receptors are disrupted then," we need to analyze the role of progesterone and its receptors in the female body, particularly in relation to pregnancy and reproductive health.

### Step-by-Step Solution:

1. **Understanding Progesterone's Role**:
- Progesterone is a hormone produced primarily by the ovaries after ovulation. It plays a crucial role in preparing the uterus for pregnancy and maintaining it.

2. **Identifying the Function of Progesterone Receptors**:
- Progesterone exerts its effects by binding to specific receptors in target tissues, including the uterus. These receptors are essential for the hormone's action.

3. **Analyzing the Options**:
- **Option 1**: "Secondary sexual characters would not be maintained."
- This option is incorrect because secondary sexual characteristics are primarily regulated by estrogen, not progesterone.

- **Option 2**: "Pituitary Gonadotropin will not be secreted."
- This option is also incorrect. While progesterone influences the menstrual cycle, the secretion of gonadotropins (LH and FSH) from the pituitary gland is primarily regulated by the hypothalamus and is not directly dependent on progesterone receptors.

- **Option 3**: "The uterus will not be able to support pregnancy."
- This option is correct. If progesterone receptors are disrupted, the uterus cannot respond to progesterone, which is essential for maintaining the uterine lining and supporting a pregnancy.

- **Option 4**: "The uterine endodermis will not begin to proliferate."
- This option is incorrect. While progesterone does play a role in preparing the endometrium, the initial proliferation of the endometrial lining is primarily stimulated by estrogen.

4. **Conclusion**:
- The correct answer is **Option 3**: "The uterus will not be able to support pregnancy."