Which of the following is not correct about nature of a hormone?

Options

A. Peptide and polypeptide
B. Steroid and iodothyronine
C. Steroids and amino acid derivative
D. Nucleic acid derivatives

Answer

To solve the question "Which of the following is not correct about the nature of a hormone?", we will analyze each option provided in the question regarding the nature of hormones.

### Step-by-Step Solution:

1. **Understanding Hormones**:
- Hormones are chemical messengers produced by glands in the endocrine system. They can be classified into different categories based on their chemical structure.

2. **Evaluating the Options**:
- **Option 1: Peptide and Polypeptide**:
- This statement is correct. Hormones can indeed be peptide hormones, which are made up of amino acids. An example is the adrenocorticotropic hormone (ACTH), which stimulates the adrenal cortex to release glucocorticoids.

- **Option 2: Steroid and Iodothyronine**:
- This statement is also correct. Steroid hormones include glucocorticoids, mineralocorticoids, and sex hormones (androgens, estrogens, and progesterone). Iodothyronines refer to thyroid hormones like thyroxine (T4) which are derived from the amino acid tyrosine and contain iodine.

- **Option 3: Steroid and Amino Acid Derivative**:
- This statement is correct as well. Steroid hormones are derived from cholesterol, while amino acid derivatives include hormones like epinephrine and norepinephrine, which are derived from the amino acid tyrosine.

- **Option 4: Nucleic Acid Derivative**:
- This statement is incorrect. Nucleic acids (DNA and RNA) are not classified as hormones. Hormones do not derive from nucleic acids; they are distinct from genetic material.

3. **Conclusion**:
- The only incorrect statement regarding the nature of hormones is **Option 4: Nucleic Acid Derivative**. Therefore, the answer to the question is Option 4.

### Final Answer:
**Option 4: Nucleic Acid Derivative is not correct about the nature of a hormone.**

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