Which of the following pair of assisted reproductive techniques involves In-vivo fertilization ?

Options

A. GIFT & ZIFT
B. ZIFT & ICSI
C. IUI & GIFT
D. IUI & ICSI

Answer

To solve the question regarding which assisted reproductive techniques involve in vivo fertilization, we can break down the options provided and analyze each one step by step.

### Step 1: Understand the Terms
- **In vivo fertilization** refers to fertilization that occurs inside the body.
- **In vitro fertilization** refers to fertilization that occurs outside the body, typically in a laboratory setting.

### Step 2: Analyze Each Technique
1. **GIFT (Gamete Intrafallopian Transfer)**:
- In GIFT, gametes (sperm and egg) are transferred directly into the fallopian tubes.
- Fertilization occurs inside the body (in vivo).
- **Conclusion**: GIFT involves in vivo fertilization.

2. **ZIFT (Zygote Intrafallopian Transfer)**:
- In ZIFT, a zygote (fertilized egg) is transferred into the fallopian tube.
- The fertilization occurs outside the body (in vitro) before the zygote is transferred.
- **Conclusion**: ZIFT does not involve in vivo fertilization.

3. **IUI (Intrauterine Insemination)**:
- In IUI, sperm is introduced directly into the uterus.
- Fertilization occurs inside the body (in vivo).
- **Conclusion**: IUI involves in vivo fertilization.

4. **ICSI (Intracytoplasmic Sperm Injection)**:
- In ICSI, a single sperm is injected directly into an egg in a laboratory setting.
- Fertilization occurs outside the body (in vitro).
- **Conclusion**: ICSI does not involve in vivo fertilization.

### Step 3: Identify the Correct Pair
Now, we look at the options provided:
- GIFT and GIFT: Both involve in vivo (correct).
- GIFT and ICSI: One is in vivo, the other is in vitro (incorrect).
- IUI and GIFT: Both involve in vivo (correct).
- IUI and ICSI: One is in vivo, the other is in vitro (incorrect).

### Final Answer
The pairs that involve in vivo fertilization are:
- **GIFT and GIFT**
- **IUI and GIFT**

However, since the question asks for a pair, the most relevant answer is:
- **IUI and GIFT**.