Cretinism is caused due to :

Options

A. Low GH from pituitary gland
B. Excessive glucocorticoids from adrenal glands
C. Low secretion of parathyroid hormone
D. Low secretion of thyroid hormones from thyroid gland

Answer

**Step-by-Step Solution:**

1. **Understanding Cretinism**: Cretinism is a condition that arises due to a deficiency in thyroid hormones during development. It is characterized by stunted growth and mental retardation.

2. **Identifying the Causes**: The question provides four options regarding the causes of Cretinism:
- Low growth hormone from the pituitary gland
- Excessive glucocorticoids from the adrenal gland
- Low secretion of parathyroid hormone
- Low secretion of thyroid hormones from the thyroid gland

3. **Analyzing Each Option**:
- **Option 1**: Low growth hormone from the pituitary gland - While growth hormone is important for growth, Cretinism specifically relates to thyroid hormone deficiency, making this option incorrect.
- **Option 2**: Excessive glucocorticoids from the adrenal gland - Excessive glucocorticoids can affect growth but are not the direct cause of Cretinism, hence this option is also incorrect.
- **Option 3**: Low secretion of parathyroid hormone - Parathyroid hormone is involved in calcium metabolism and does not directly relate to Cretinism, making this option incorrect.
- **Option 4**: Low secretion of thyroid hormones from the thyroid gland - This is the correct cause of Cretinism, as a deficiency in thyroid hormones (T3 and T4) leads to the symptoms associated with this condition.

4. **Conclusion**: The correct answer is that Cretinism is caused due to low secretion of thyroid hormones from the thyroid gland.

**Final Answer**: Low secretion of thyroid hormones from the thyroid gland.

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