Choose the wrong statement from the following.

Options

A. Failure of segragation of chromatides during cell divisin result in aneuploidy
B. Additional copy of 'X'b chromosome in male result in Klinefelter's syndrome.
C. Closely located genes in a chromosome always assort independently resulting in recombinations
D. Failure of cytokinesis after DNA replication results in polyploidy

Answer

To solve the question "Choose the wrong statement from the following," we will analyze each option provided to identify the incorrect one.

### Step-by-Step Solution:

1. **Understanding the Question**: We need to identify which of the statements provided is incorrect regarding genetic concepts.

2. **Analyzing Option 1**:
- **Statement**: "Failure of the segregation of chromatids during cell division resulting in aneuploidy."
- **Analysis**: This statement is correct. Aneuploidy occurs when there is an error in the segregation of chromosomes during cell division, leading to an abnormal number of chromosomes.

3. **Analyzing Option 2**:
- **Statement**: "Additional copy of X chromosome in male results in Klinefelter syndrome."
- **Analysis**: This statement is also correct. Klinefelter syndrome is characterized by the presence of an extra X chromosome in males (XXY), leading to various developmental issues.

4. **Analyzing Option 3**:
- **Statement**: "Closely located genes in a chromosome always assort independently resulting in recombinations."
- **Analysis**: This statement is incorrect. Genes that are closely located on the same chromosome tend to be inherited together (linked) and do not assort independently. This is contrary to Mendel's law of independent assortment.

5. **Analyzing Option 4**:
- **Statement**: "Failure of cytokinesis after DNA replication results in polyploidy."
- **Analysis**: This statement is correct. Polyploidy occurs when there is a failure in cytokinesis, leading to cells with multiple sets of chromosomes.

6. **Conclusion**: Based on the analysis, the wrong statement is **Option 3**.

### Final Answer:
The wrong statement is **Option 3: "Closely located genes in a chromosome always assort independently resulting in recombinations."**