During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called ?

Options

A. CAAT box
B. GGTT box
C. AAAT box
D. TATA box

Answer

D

Explanation

TATA box is present in eukaryotic promoter region . It has a resemblance with Pribnow box of prokaryotes . TATA box was identified by Dr. Hogness and so , it is also called as Hogness box It is a 7 bp long region located 20 bp upstream to the start point.
During the prcess of transcription the RNA polymerase ( a holenzyme which has a core unit and a sigma factor for proper initiation of transcription) binds to TATA box due to which DNA assumes a saddle like structure at this place.