Why is it not possible for an alien DNA to become part of a chromosome anywhere along its length and replicate normally ?

Why is it not possible for an alien DNA to become part of chromosome anywhere along its length and replicate?

Assertion : If any piece of DNA is somehow transferred into an alien organism,, most likely, this piece of DNA would not be able to multiple itself in the progeny cells of the organism Reason :For the multiplication of any alien piece of DNA in an organism it needs to be a part of a chromosome (s) which has a specific sequence known as origin of replication.

In which phase of the cell cycle DNA doubles and chromosomes replicate ?

During replication of a bacterial chromosome DNA synthesis stars from a replication origin site and

During replication of a bacterial chromosomes, DNA synthesis starts from a replication origin site and

When an alien DNA is linked with the origin of replication, so that this alien piece of DNA can replicate and multiply itself in the host organism, then this can be called as