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Why does the lac operon shut down some t...

Why does the lac operon shut down some time after the addition of lactose in the medium where E.coli was growing ? Why low level expression of lac operon is always required ?

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Lac operon has polycistronic structural gene i.e., z, y, a adjacent to an operator, a promoter and a regulator.
`**" "`Lactose is the inducer that inactivates repressor, after addition of lactose, `beta-` galactosidese breaks lactose to galactose and glucose. Therefore, there is no more lactose to bind to the repressor protein and the lac operon shuts down.
`**" "`A very low level of expression of lac operon has to be present in the cell all the time, otherwise lactose cannot enter the cells.
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Assertion :- Lactose is the substrate for the enzyme beta -galactosidse & it regulates switching on & off of the operon. Reson: A very low level of expression of lac operon is always present in cell all the time.

The operon is a unit of gene expression. Lac operon in E. coli is an inducible control.

How would lac operon operate in E. coli growing in a culture medium where lactose is present as source of sugar ?

In the function of the lac operon in E-coli, the lac genes z, y, a are transcribed in the presence of lactose because

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Write the different components of a lac - operon in E . Coli Explain its expression while in an 'open' state.

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