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Why is RNA more reactive in comparison t...

Why is RNA more reactive in comparison to DNA ?

Text Solution

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OH-bond in the ribose of RNA makes the molecule more reactive, compared with DNA. RNA is not stable under alkaline conditions, plus the large grooves.
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Knowledge Check

  • Assertion. DNA is more stable while RNA is more reactive. Reason. DNA was first discovered by Watson and Crick (1953).

    A
    If both A and R are true and R is the correct explanation of A.
    B
    If both A and R are true but R is not the correct explanation of A.
    C
    If A is true but R is false.
    D
    If both A and R are false.

  • RNA is more reactive or unstable to DNA due to presence of :-

    A
    `-OH` group on `2^(nd)` position of ribose sugar
    B
    `-OH` group on `3^(rd)` position of deoxy ribose sugar
    C
    `-` Phosphate group on `5^(th)` position of ribose sugar
    D
    `-OH` group on `1^(st)` position of ribose sugar

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