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How does recombinant DNA technology help...

How does recombinant DNA technology help in treating haemophilia patients?

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(i) Clotting factor VIII isolated from blood of normal human being was used in the treatment of Haemophilia A.
(ii) Requirement of large quantities of blood for this purpose and the risk of transmission of infections diseases like AIDS is a disadvantage.
(iii) Recombinant DNA technology was used to produce Recombinant Factor VIII in the Chinese Hamster ovary and in the baby Hamster kidney cells.
(iv) Recently a cell line of human origin has been used to produce Human blood, clotting factor VIII for the first time.
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