Which of the following is proper sequence of stages in mitosis?

Options

A. Metaphase, telophase, prophase and anaphase
B. Prophase, metaphase, anaphase and telophase
C. Anaphase, metaphase, telophase and prophase
D. Telophase, anaphase, metaphase and prophase

Answer

To determine the proper sequence of stages in mitosis, we need to understand the order of the phases involved. Mitosis is a process that divides a single cell into two identical daughter cells, and it consists of several distinct stages. Here’s the step-by-step solution:

### Step-by-Step Solution:

1. **Identify the Stages of Mitosis**:
The stages of mitosis are:
- Prophase
- Metaphase
- Anaphase
- Telophase

2. **Understand Each Stage**:
- **Prophase**: The chromatin condenses into visible chromosomes, and the nucleolus disappears. The spindle apparatus begins to form.
- **Metaphase**: The chromosomes align at the cell's equator, known as the metaphase plate.
- **Anaphase**: The centromeres split, and the sister chromatids are pulled apart towards opposite poles of the cell.
- **Telophase**: The chromosomes reach the poles, the nuclear membrane re-forms around each set of chromosomes, and the nucleolus reappears.

3. **Sequence the Stages**:
The correct sequence of stages in mitosis is:
- Prophase → Metaphase → Anaphase → Telophase

4. **Select the Correct Option**:
Based on the identified sequence, the correct answer is the option that lists these stages in the order: Prophase, Metaphase, Anaphase, and Telophase.

### Conclusion:
The proper sequence of stages in mitosis is **Prophase, Metaphase, Anaphase, and Telophase**. Therefore, the correct answer is **Option 2**.

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