`G_(0)` -phase of cell denotes

Options

A. Exit of cell from cell cycle
B. Check point before entering the next phase
C. Death of cell
D. Temporary pause

Answer

To solve the question regarding what the G₀ phase of the cell denotes, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Cell Cycle**:
- The cell cycle consists of several phases: G1, S, G2, and M phase. The G₀ phase is a part of this cycle.

2. **Defining the G₀ Phase**:
- The G₀ phase is often referred to as a resting or quiescent phase. Cells in this phase are not actively dividing or preparing to divide.

3. **Identifying Characteristics of G₀ Phase**:
- Cells may enter the G₀ phase from the G1 phase when conditions are not favorable for division. This can happen due to various factors such as nutrient availability, cell size, or DNA integrity.

4. **Analyzing the Options**:
- The question provides multiple options regarding what the G₀ phase denotes. We need to evaluate each option:
- **Option 1**: "Exit of the cell from the cell cycle" - This is correct. Cells in G₀ are effectively in a state of exit from the active cell cycle.
- **Option 2**: "A checkpoint before entering the next phase" - This is incorrect. Checkpoints occur in other phases, like G2.
- **Option 3**: "Temporary pause" - This is misleading as G₀ is not merely a temporary pause; it can be a long-term state.
- **Option 4**: "None of the above" - This is incorrect since option 1 is valid.

5. **Conclusion**:
- Based on the analysis, the G₀ phase denotes the exit of the cell from the cell cycle, making **Option 1** the correct answer.

### Final Answer:
The G₀ phase of the cell denotes the exit of the cell from the cell cycle.

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