The chromosome contains two chromatids from

Options

A. End of S phase to end of Metaphase
B. Beginning of `G_(2)` phase to end of anaphase
C. Beginning of prophase to beginning of anaphase
D. End of `G_(1)` phase to end of anaphase

Answer

To answer the question "The chromosome contains two chromatids from?", we need to analyze the stages of the cell cycle and the behavior of chromosomes during these stages.

### Step-by-Step Solution:

1. **Understanding Chromatid Formation**:
- During the **S phase** (Synthesis phase) of the cell cycle, DNA replication occurs. Each chromosome is duplicated, resulting in two identical copies called sister chromatids, which are joined at a region called the centromere.

2. **Identifying Relevant Phases**:
- After the S phase, the cell enters the **G2 phase** (Gap 2 phase), where it prepares for mitosis. At this point, each chromosome consists of two sister chromatids.
- The cell then proceeds to the **M phase** (Mitosis), where the chromosomes align and are prepared for separation.

3. **Chromatid Status During Mitosis**:
- During **metaphase**, the chromosomes are aligned at the metaphase plate, and they still consist of two chromatids.
- As the cell enters **anaphase**, the centromeres split, and the sister chromatids are pulled apart to opposite poles of the cell. At this point, they are no longer considered sister chromatids but are now individual chromosomes.

4. **Conclusion**:
- Therefore, the correct answer to the question is that chromosomes contain two chromatids from the end of the **S phase** to the end of **metaphase**.

### Final Answer:
The chromosome contains two chromatids from the end of the S phase to the end of the metaphase.

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