Nuclear envelope, E.R, Golgi complex and nucleolus disapper respectively during

Options

A. Early prophase and early Telophase
B. Early Metaphase and late Anaphase
C. Late prophase and Late Telophase
D. Late Metaphase and early Anaphase

Answer

To solve the question regarding when the nuclear envelope, endoplasmic reticulum (E.R), Golgi complex, and nucleolus disappear during the cell cycle, we can analyze the stages of mitosis. Here’s a step-by-step breakdown:

### Step-by-Step Solution:

1. **Understanding the Question**:
- We need to identify the specific phases of mitosis during which the nuclear envelope, E.R, Golgi complex, and nucleolus disappear.

2. **Phases of Mitosis**:
- Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.

3. **Nuclear Envelope**:
- The nuclear envelope begins to break down during **prophase**. By the end of **prophase**, it is completely disassembled.

4. **Endoplasmic Reticulum (E.R)**:
- The E.R also starts to break down during **prophase** and is generally not visible by the time the cell reaches **metaphase**.

5. **Golgi Complex**:
- Similar to the E.R, the Golgi complex disassembles during **prophase** and is not present during metaphase.

6. **Nucleolus**:
- The nucleolus disappears during **prophase** as well, coinciding with the breakdown of the nuclear envelope.

7. **Identifying the Correct Phase**:
- By analyzing the phases, we can conclude that all these structures (nuclear envelope, E.R, Golgi complex, and nucleolus) disappear during **late prophase** and are not present during **metaphase**.

8. **Conclusion**:
- Therefore, the correct answer to the question is that the nuclear envelope, E.R, Golgi complex, and nucleolus disappear respectively during **late prophase** and early **metaphase**.

### Final Answer:
The nuclear envelope, E.R, Golgi complex, and nucleolus disappear respectively during **late prophase** and early **metaphase**.

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