Initiation of condensation of chromosomal material takes place is

Options

A. Prophase
B. Metaphase
C. Anaphase
D. Telophase

Answer

To determine in which phase the initiation of condensation of chromosomal material takes place, we need to analyze the different phases of mitosis.

### Step-by-Step Solution:

1. **Understanding the Phases of Mitosis**: Mitosis consists of several phases: Prophase, Metaphase, Anaphase, and Telophase. Each phase has distinct characteristics.

2. **Identifying Prophase**: Prophase is the first phase of mitosis. During this phase, the chromatin (the material that makes up chromosomes) begins to condense and becomes visible as distinct chromosomes. This is where the initiation of condensation occurs.

3. **Examining Metaphase**: In Metaphase, the chromosomes are aligned at the cell's equator. While the chromosomes are clearly visible, the condensation process has already occurred, so this phase does not initiate condensation.

4. **Looking at Anaphase**: During Anaphase, the sister chromatids are pulled apart and move towards opposite poles of the cell. This phase does not involve the initiation of condensation but rather separation of already condensed chromosomes.

5. **Considering Telophase**: In Telophase, the chromosomes begin to de-condense back into chromatin, and the nuclear membrane reforms. This phase also does not involve the initiation of condensation.

6. **Conclusion**: Based on the analysis, the initiation of condensation of chromosomal material takes place in **Prophase**.

### Final Answer:
The initiation of condensation of chromosomal material takes place in **Prophase**.

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