Mark the correct statement in the followings

Options

A. Injecting microbes during immunization induces passive immunity
B. Cell-mediated immune response is responsible for graft rejection
C. Colostrum during initial days of lactation provides active immunity to infant.
D. None of these

Answer

To answer the question "Mark the correct statement in the following," we will analyze each statement provided and determine which one is correct.

### Step-by-Step Solution:

1. **Evaluate Statement A**:
- **Statement**: "Injecting microbes during immunization induces passive immunity."
- **Analysis**: During immunization (vaccination), we do not inject live microbes directly. Instead, we use killed or attenuated microbes. Passive immunity occurs when preformed antibodies are injected into a patient, not when the immune system is stimulated to produce its own antibodies. Therefore, this statement is incorrect.

2. **Evaluate Statement B**:
- **Statement**: "Self-mediated immune response is responsible for graft rejection."
- **Analysis**: This statement is correct. Graft rejection occurs when the recipient's immune system recognizes the donor organ as foreign. T cells are responsible for this self-mediated immune response, leading to the rejection of the graft. Thus, this statement is correct.

3. **Evaluate Statement C**:
- **Statement**: "Colostrum during initial days of lactation provides active immunity to the infant."
- **Analysis**: Colostrum is the first milk produced by the mother after giving birth and is rich in antibodies, particularly IgA. It provides passive immunity to the infant because it contains preformed antibodies transferred from the mother, rather than stimulating the infant's immune system to produce its own antibodies. Therefore, this statement is incorrect.

4. **Conclusion**:
- The only correct statement is **Statement B**: "Self-mediated immune response is responsible for graft rejection."

### Final Answer:
The correct statement is: **Self-mediated immune response is responsible for graft rejection.**

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