The agents which can cause neoplastic cell generation are

Options

A. Gamma rays
B. X-rays
C. UV rays
D. All of these

Answer

### Step-by-Step Solution:

1. **Understanding Neoplastic Cells**:
- Neoplastic cells are abnormal cells that grow uncontrollably, forming tumors. These cells lose the normal regulatory mechanisms that control cell growth, such as contact inhibition.

2. **Identifying Agents that Cause Neoplastic Cell Generation**:
- Various agents can induce mutations in normal cells, leading to the formation of neoplastic cells. These agents can be classified into several categories, including physical, chemical, and biological agents.

3. **Physical Agents**:
- **Gamma Rays**: High-energy radiation that can cause mutations in the DNA of normal cells, leading to uncontrolled growth.
- **X-rays**: Another form of ionizing radiation that can damage DNA and potentially lead to cancer.
- **Ultraviolet (UV) Rays**: Known to cause skin cancer by inducing mutations in skin cells.

4. **Chemical Agents**:
- Certain chemicals, known as carcinogens, can also lead to neoplastic cell generation. These include substances like tobacco smoke, asbestos, and various industrial chemicals.

5. **Biological Agents**:
- Some viruses and bacteria can cause cancer. For example, the Human Papillomavirus (HPV) is linked to cervical cancer, and Hepatitis B and C viruses are associated with liver cancer.

6. **Conclusion**:
- The agents that can cause neoplastic cell generation include gamma rays, X-rays, UV rays, and various chemical and biological agents. Therefore, the answer encompasses all these factors.