What other advantage has HMS over Krebs cycle?

Options

A. It release more `CO_(2)`
B. It release more energy
C. It produce more `NADH_(2)` molecules
D. None of these

Answer

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks for an advantage of the Hexose Monophosphate Shunt (HMS) over the Krebs Cycle.

2. **Identifying the Hexose Monophosphate Shunt**: The HMS, also known as the Pentose Phosphate Pathway, is an alternative pathway for carbohydrate metabolism. It primarily functions to produce ribose sugars and NADPH.

3. **Key Products of HMS**: One of the main products of the HMS is ribose-5-phosphate, which is crucial for the synthesis of nucleic acids (DNA and RNA). Additionally, it produces glycolytic intermediates like glyceraldehyde-3-phosphate and fructose-6-phosphate.

4. **Comparison with Krebs Cycle**: The Krebs Cycle (or Citric Acid Cycle) is primarily involved in energy production through the oxidation of acetyl-CoA, generating ATP, NADH, and FADH2. However, it does not produce ribose sugars.

5. **Conclusion**: The major advantage of the HMS over the Krebs Cycle is its ability to produce ribose sugars, which are essential for nucleic acid synthesis, while the Krebs Cycle does not provide this function.

6. **Final Answer**: The correct answer is that the HMS provides ribose sugar for nucleic acid synthesis, which is an advantage over the Krebs Cycle.