How many ATPs are consumed in HMS?

Options

A. Two
B. Three
C. Four
D. One

Answer

To determine how many ATPs are consumed in the Hexose Monophosphate Shunt (HMS), we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the HMS**: The Hexose Monophosphate Shunt, also known as the Pentose Phosphate Pathway, is a metabolic pathway parallel to glycolysis. It primarily serves to generate NADPH and ribose-5-phosphate for nucleotide synthesis.

2. **ATP Consumption in HMS**: In the HMS, one molecule of glucose-6-phosphate is converted into ribulose-5-phosphate. During this conversion, one ATP molecule is consumed.

3. **Total ATP Yield**: While the HMS produces NADPH, it does not produce ATP directly. However, it is important to note that the overall process of glucose metabolism can yield ATP. In the context of the question, we are only concerned with ATP consumption.

4. **Final Calculation**: Since 1 ATP is consumed in the conversion of glucose-6-phosphate to ribulose-5-phosphate, the total ATP consumed in the HMS is 1.

5. **Conclusion**: Therefore, the answer to the question "How many ATPs are consumed in HMS?" is 1 ATP.

### Final Answer:
**1 ATP is consumed in the Hexose Monophosphate Shunt (HMS).**

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