Arber, Nathans and Smith received Nobel prize in 1978 for pathbreaking work in the field of

Options

A. PCR
B. Restriction endonuclease enzymes
C. ELISA
D. Western blotting

Answer

**Step-by-Step Text Solution:**

1. **Identify the Scientists**: The question asks about the Nobel Prize winners in 1978, specifically mentioning Arber, Nathans, and Smith.
- **Hint**: Remember the full names and nationalities of the scientists: Werner Arber (Swiss), Daniel Nathans (American), and Hamilton O. Smith (American).

2. **Determine the Field of Work**: The next step is to identify the specific field in which these scientists made significant contributions.
- **Hint**: Consider the options provided: PCR, Restriction Endonuclease Enzyme, ELISA, and Western Blot. Think about which of these relates to the work of the mentioned scientists.

3. **Understand Their Contribution**: These scientists are known for their discovery of restriction endonucleases, which are enzymes that cut DNA at specific sites. This discovery was crucial for the development of recombinant DNA technology.
- **Hint**: Recall that restriction enzymes are essential tools in molecular biology for manipulating DNA.

4. **Confirm the Nobel Prize Category**: They were awarded the Nobel Prize in Physiology or Medicine for their work, which highlights the significance of their discovery in biological sciences.
- **Hint**: The Nobel Prize in Physiology or Medicine often recognizes groundbreaking discoveries in the life sciences.

5. **Select the Correct Option**: Based on the information gathered, the correct answer to the question is Option 2: Restriction Endonuclease Enzyme.
- **Hint**: Eliminate the other options by considering their relevance to the contributions of Arber, Nathans, and Smith.

**Final Answer**: Arber, Nathans, and Smith received the Nobel Prize in 1978 for their work on Restriction Endonuclease Enzymes.

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