Which enzymeis secreted from endothelial wall of capilaries and breaks the chylomicrons into fatty acids and glycerol

Options

A. gastric lipase
B. lingual lipase
C. lipoprotein lipase
D. pancreatic lipase

Answer

To answer the question regarding which enzyme is secreted from the endothelial wall of capillaries and breaks down chylomicrons into fatty acids and glycerol, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Chylomicrons**:
- Chylomicrons are lipoprotein particles that transport dietary lipids from the intestines to other locations in the body. They are primarily composed of triglycerides, cholesterol, and proteins.

2. **Role of Enzymes in Lipid Digestion**:
- Various lipases are involved in the digestion of lipids. These include gastric lipase, lingual lipase, pancreatic lipase, and lipoprotein lipase. Each of these enzymes has a specific role in breaking down triglycerides into fatty acids and glycerol.

3. **Identifying the Enzyme in Question**:
- The question specifically asks for the enzyme secreted from the endothelial wall of capillaries.
- Among the options provided:
- **Gastric lipase**: Secreted in the stomach, acts on lipids but not in capillaries.
- **Lingual lipase**: Secreted in the mouth, acts on lipids during the initial digestion.
- **Pancreatic lipase**: Secreted by the pancreas, plays a major role in lipid digestion in the small intestine.
- **Lipoprotein lipase**: Secreted from the endothelial cells of capillaries, specifically acts on chylomicrons and very-low-density lipoproteins (VLDL).

4. **Function of Lipoprotein Lipase**:
- Lipoprotein lipase is crucial for hydrolyzing triglycerides in chylomicrons into free fatty acids and glycerol, allowing these components to be absorbed by tissues.

5. **Conclusion**:
- Based on the above analysis, the enzyme that is secreted from the endothelial wall of capillaries and breaks down chylomicrons into fatty acids and glycerol is **lipoprotein lipase**.

### Final Answer:
The correct answer is **lipoprotein lipase**.

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