Which of the following statement is not correct?

Options

A. Acini are present in the pancreas and secreate carboxypeptidese
B. Brunner's galnds are present in the submucosa of stomach and secrete pepsinogen
C. Goblet cells are present in the mucosa of intestine and secrete mucus
D. Oxyntic cells are present in the mucosa of stomach and secrete HCl

Answer

To determine which statement is not correct, we will analyze each option one by one:

1. **SNI are present in the pancreas**:
- SNI refers to the "Islets of Langerhans" in the pancreas. These are clusters of cells that secrete hormones, not digestive enzymes. However, the statement mentions that they secrete enzymes, which is incorrect. The pancreas does secrete digestive enzymes, but these are produced by acinar cells, not the Islets of Langerhans. Therefore, this statement is partially correct but misleading in the context of enzyme secretion.

2. **Brunner's gland is present in submucosa**:
- Brunner's glands are indeed located in the submucosa of the duodenum (the first part of the small intestine). They secrete alkaline mucus to neutralize gastric acid. This statement is correct.

3. **Goblet cells are present in the mucosa of the intestine and secrete mucus**:
- Goblet cells are specialized epithelial cells found in the mucosal lining of the intestines (and other organs) that secrete mucus. This statement is correct.

4. **Exocrine cells are present in the mucosa of the stomach and secrete HCl**:
- The cells that secrete hydrochloric acid (HCl) in the stomach are called parietal cells, which are indeed located in the gastric mucosa. This statement is also correct.

After analyzing all the statements, the second statement regarding Brunner's gland is the only one that is incorrect in the context provided, as it incorrectly states that Brunner's gland is present in the submucosa of the stomach instead of the duodenum.

### Final Answer:
The incorrect statement is: **Brunner's gland is present in the submucosa of the stomach and secretes pepsinogen.**