Which of the following sequences represents the correct order in which filtrate would move through the nephron during urine formation ?

Options

A. Renal corpuscle, loop of Henle, distal convoluted tubule, collecting duct
B. Collecting duct, distal convoluted tubule, rnal corpuscle, loop of Henle
C. Renal corpuscle, distant covoluted tubule, collecting duct, loop of Henle
D. Renal corpuscle, distal convoluted tubule, loop of Henle, collecting duct

Answer

To determine the correct order in which filtrate moves through the nephron during urine formation, we need to understand the structure and function of the nephron. The nephron is the functional unit of the kidney, and it consists of several parts through which the filtrate passes. Here’s the step-by-step solution:

### Step-by-Step Solution:

1. **Renal Corpuscle**: The process begins in the renal corpuscle, which consists of the glomerulus (a network of capillaries) and Bowman's capsule. Blood is filtered here, and the filtrate enters Bowman's capsule.

2. **Proximal Convoluted Tubule (PCT)**: After the renal corpuscle, the filtrate moves into the proximal convoluted tubule. Here, reabsorption of water, ions, and nutrients occurs.

3. **Loop of Henle**: The filtrate then travels down into the Loop of Henle, which has a descending limb and an ascending limb. This structure is crucial for the concentration of urine.

4. **Distal Convoluted Tubule (DCT)**: Following the Loop of Henle, the filtrate moves into the distal convoluted tubule. Additional reabsorption and secretion occur here.

5. **Collecting Duct**: Finally, the filtrate enters the collecting duct, where it is further concentrated and ultimately becomes urine before being excreted from the kidney.

### Correct Order:
- Renal Corpuscle → Proximal Convoluted Tubule → Loop of Henle → Distal Convoluted Tubule → Collecting Duct

### Conclusion:
The correct sequence representing the movement of filtrate through the nephron during urine formation is:
- **Renal Corpuscle → Loop of Henle → Distal Convoluted Tubule → Collecting Duct** (Option 1).